Differential immune regulation of activated T cells between cutaneous and mucosal leishmaniasis as a model for pathogenesis

SUMMARY Cutaneous (CL) and mucosal leishmaniasis (ML) are characterized by a predominant type 1 immune response (IFN-γ and TNF-α production) and strong inflammatory response in the lesions with few parasites. This exacerbated type 1 response is more evident in ML as compared to CL. Our main hypothes...

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Main Authors: CARVALHO, L. P., PASSOS, S., BACELLAR, O., LESSA, M., ALMEIDA, R. P., MAGALHÃES, A., DUTRA, W. O., GOLLOB, K. J., MACHADO, P., DE JESUS, A. Ribeiro
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593461/
https://ncbi.nlm.nih.gov/pubmed/17430548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3024.2007.00940.x
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