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Liposomes, lipid A, and aluminum hydroxide enhance the immune response to a synthetic malaria sporozoite antigen.

A liposome-encapsulated cloned protein (R32tet32) containing sequences from the tetrapeptide repeat region of the circumsporozoite protein of Plasmodium falciparum sporozoites was examined for immunogenicity with rabbits and monkeys. Effects of adjuvants were tested by encapsulation of the antigen i...

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Autors principals: Richards, R L, Hayre, M D, Hockmeyer, W T, Alving, C R
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC259345/
https://ncbi.nlm.nih.gov/pubmed/3277918
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