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Altered Oligomerization Properties of N316 Mutants of Escherichia coli TyrR

The transcriptional regulator TyrR is known to undergo a dimer-to-hexamer conformational change in response to aromatic amino acids, through which it controls gene expression. In this study, we identified N316D as the second-site suppressor of Escherichia coli TyrR(E274Q), a mutant protein deficient...

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Detalhes bibliográficos
Main Authors: Koyanagi, Takashi, Katayama, Takane, Suzuki, Hideyuki, Kumagai, Hidehiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593242/
https://ncbi.nlm.nih.gov/pubmed/18931124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00889-08
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