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Contextual memory deficits observed in mice overexpressing small conductance Ca(2+)-activated K(+) type 2 (K(Ca)2.2, SK2) channels are caused by an encoding deficit
Hippocampal-dependent synaptic plasticity and memory are modulated by apamin-sensitive small conductance Ca(2+)-activated K(+) (SK) channels. Transgenic mice overexpressing SK2 channels (SK2+/T mice) exhibit marked deficits in hippocampal memory and synaptic plasticity, as previously reported. Here,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593144/ https://ncbi.nlm.nih.gov/pubmed/18385475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.906808 |
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