ESI-MS Characterization of a Novel Pyrrole-Inosine Nucleoside that Interacts with Guanine Bases

Based on binding studies undertaken by electrospray ionization-mass spectrometry, a synthetic pyrrole-inosine nucleoside, 1, capable of forming an extended three-point Hoogsteen-type hydrogen-bonding interaction with guanine, is shown to form specific complexes with two different quadruplex DNA stru...

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Bibliografiske detaljer
Main Authors: Pierce, Sarah E., Sherman, Courtney L., Jayawickramarajah, Janarthanan, Lawrence, Candace M., Sessler, Jonathan L., Brodbelt, Jennifer S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593082/
https://ncbi.nlm.nih.gov/pubmed/18790136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2008.04.018
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