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Combinatorial Gene Therapy with BMP2/7 Enhances Cranial Bone Regeneration

BMP2/7 heterodimer expression by adenovirus can stimulate bone formation at subcutaneous sites. In the present study, we evaluate whether this approach will also promote healing of cranial defects. Adenovirus expressing BMP2 or BMP7 (AdBMP2, AdBMP7) was titrated to yield equivalent BMP protein level...

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Autors principals: Koh, J.T., Zhao, Z., Wang, Z., Lewis, I.S., Krebsbach, P.H., Franceschi, R.T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593032/
https://ncbi.nlm.nih.gov/pubmed/18719211
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