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Characterization of aromatic- and purine-dependent Salmonella typhimurium: attention, persistence, and ability to induce protective immunity in BALB/c mice.

Stable transposon-generated auxotrophic mutations in aroA, purA, and purE or aroA and purA together were introduced into Salmonella typhimurium strains which were virulent in mice. Strains harboring any of these mutations were attenuated when tested in BALB/c mice. purE strains were less attenuated...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: O'Callaghan, D, Maskell, D, Liew, F Y, Easmon, C S, Dougan, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3276625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.2.419-423.1988
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