Characterization of aromatic- and purine-dependent Salmonella typhimurium: attention, persistence, and ability to induce protective immunity in BALB/c mice.

Stable transposon-generated auxotrophic mutations in aroA, purA, and purE or aroA and purA together were introduced into Salmonella typhimurium strains which were virulent in mice. Strains harboring any of these mutations were attenuated when tested in BALB/c mice. purE strains were less attenuated...

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Autores principales: O'Callaghan, D, Maskell, D, Liew, F Y, Easmon, C S, Dougan, G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC259298/
https://ncbi.nlm.nih.gov/pubmed/3276625
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