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Lysine-Enriched Cecropin-Mellitin Antimicrobial Peptides with Enhanced Selectivity
Lysine-enriched analogs of the cecropin-mellitin hybrid peptide, CA(1-7) M(2-9) (designated CM15), designed with optimized amphipathicity, retained antimicrobial activities similar to that of wild-type CM15 and had substantially reduced levels of hemolytic activity and cytotoxicity toward cultured m...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592880/ https://ncbi.nlm.nih.gov/pubmed/18852279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00810-08 |
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