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Bacteriophage Therapy and the Mutant Selection Window
We use kinetic models to investigate how to design antimicrobial phage therapies to minimize emergence of resistant bacteria. We do this by modifying the “mutant selection window” hypothesis in a way that accounts for the ongoing self-replication of the phage. We show that components of combination...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592868/ https://ncbi.nlm.nih.gov/pubmed/18838590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00574-08 |
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