Complex Ciprofloxacin Resistome Revealed by Screening a Pseudomonas aeruginosa Mutant Library for Altered Susceptibility

Pseudomonas aeruginosa offers substantial therapeutic challenges due to its high intrinsic resistance to many antibiotics and its propensity to develop mutational and/or adaptive resistance. The PA14 comprehensive mutant library was screened for mutants exhibiting either two- to eightfold increased...

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Main Authors: Breidenstein, Elena B. M., Khaira, Bhavjinder K., Wiegand, Irith, Overhage, Joerg, Hancock, Robert E. W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592849/
https://ncbi.nlm.nih.gov/pubmed/18824609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00222-08
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