μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans

Synaptic vesicles must be recycled to sustain neurotransmission, in large part via clathrin-mediated endocytosis. Clathrin is recruited to endocytic sites on the plasma membrane by the AP2 adaptor complex. The medium subunit (μ2) of AP2 binds to cargo proteins and phosphatidylinositol-4,5-bisphospha...

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Main Authors: Gu, Mingyu, Schuske, Kim, Watanabe, Shigeki, Liu, Qiang, Baum, Paul, Garriga, Gian, Jorgensen, Erik M.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592831/
https://ncbi.nlm.nih.gov/pubmed/19047463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806088
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