Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis

Cytoplasmic dynein functions at several sites during mitosis; however, the basis of targeting to each site remains unclear. Tandem mass spectrometry analysis of mitotic dynein revealed a phosphorylation site in the dynein intermediate chains (ICs) that mediates binding to kinetochores. IC phosphoryl...

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Détails bibliographiques
Auteurs principaux: Whyte, Jacqueline, Bader, Jason R., Tauhata, Sinji B.F., Raycroft, Maurice, Hornick, Jessica, Pfister, K. Kevin, Lane, William S., Chan, Gordon K., Hinchcliffe, Edward H., Vaughan, Patricia S., Vaughan, Kevin T.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2008
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592828/
https://ncbi.nlm.nih.gov/pubmed/19029334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804114
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