Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region

INTRODUCTION: Recent studies identified STAT4 (signal transducers and activators of transcription-4) as a susceptibility gene for systemic lupus erythematosus (SLE). STAT1 is encoded adjacently to STAT4 on 2q32.2-q32.3, upregulated in peripheral blood mononuclear cells from SLE patients, and functio...

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Détails bibliographiques
Auteurs principaux: Kawasaki, Aya, Ito, Ikue, Hikami, Koki, Ohashi, Jun, Hayashi, Taichi, Goto, Daisuke, Matsumoto, Isao, Ito, Satoshi, Tsutsumi, Akito, Koga, Minori, Arinami, Tadao, Graham, Robert R, Hom, Geoffrey, Takasaki, Yoshinari, Hashimoto, Hiroshi, Behrens, Timothy W, Sumida, Takayuki, Tsuchiya, Naoyuki
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592800/
https://ncbi.nlm.nih.gov/pubmed/18803832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2516
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