The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation

INTRODUCTION: The treatment of septic conditions in critically ill patients is still one of medicine's major challenges. Cyclic nucleotides, adenosine and its receptors play a pivotal role in the regulation of inflammatory responses and in limiting inflammatory tissue destruction. The aim of th...

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Main Authors: Kayhan, Nalan, Funke, Benjamin, Conzelmann, Lars Oliver, Winkler, Harald, Hofer, Stefan, Steppan, Jochen, Schmidt, Heinfried, Bardenheuer, Hubert, Vahl, Christian-Friedrich, Weigand, Markus A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592762/
https://ncbi.nlm.nih.gov/pubmed/18847498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7033
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