Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis

INTRODUCTION: We performed a study to determine whether an enrollment sequence effect noted in the PROWESS (recombinant human activated Protein C Worldwide Evaluation in Severe Sepsis) trial exists in the ADDRESS (Administration of Drotrecogin Alfa [Activated] [DrotAA] in Early Stage Severe Sepsis)...

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Hlavní autoři: Laterre, Pierre-François, Macias, William L, Janes, Jonathan, Williams, Mark D, Nelson, David R, Girbes, Amand RJ, Dhainaut, Jean-François, Abraham, Edward
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592745/
https://ncbi.nlm.nih.gov/pubmed/18786266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7011
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