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Multiple Doses of Erythropoietin Impair Liver Regeneration by Increasing TNF-α, the Bax to Bcl-xL Ratio and Apoptotic Cell Death

BACKGROUND: Liver resection and the use of small-for-size grafts are restricted by the necessity to provide a sufficient amount of functional liver mass. Only few promising strategies to maximize liver regeneration are available. Apart from its erythropoiesis-stimulating effect, erythropoietin (EPO)...

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Detalhes bibliográficos
Main Authors: Klemm, Katja, Eipel, Christian, Cantré, Daniel, Abshagen, Kerstin, Menger, Michael D., Vollmar, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592699/
https://ncbi.nlm.nih.gov/pubmed/19079544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003924
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