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Farnesylation of Ydj1 Is Required for In Vivo Interaction with Hsp90 Client Proteins

Ydj1 of Saccharomyces cerevisiae is an abundant cytosolic Hsp40, or J-type, molecular chaperone. Ydj1 cooperates with Hsp70 of the Ssa family in the translocation of preproteins to the ER and mitochondria and in the maturation of Hsp90 client proteins. The substrate-binding domain of Ydj1 directly i...

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Hlavní autoři: Flom, Gary A., Lemieszek, Marta, Fortunato, Elizabeth A., Johnson, Jill L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592663/
https://ncbi.nlm.nih.gov/pubmed/18829866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-04-0435
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