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The Critical Role of TGF-β1 in the Development of Induced Foxp3+ Regulatory T Cells

Foxp3+T regulatory cell (Treg) subsets play a crucial role in the maintenance of immune homeostasis against self-antigen. The lack or dysfunction of these cells is responsible for the pathogenesis and development of many autoimmune diseases. Therefore, manipulation of these cells may provide a novel...

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Autor principal: Zheng, Song Guo
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592590/
https://ncbi.nlm.nih.gov/pubmed/19079658
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