Early growth response genes regulate B cell development, proliferation and immune response

SUMMARY: Egr-1 (Early growth response gene-1) is an immediate early gene encoding a zinc finger motif containing transcription factor. Upon cross-linking of B cell receptor (BCR), mature B cells undergo proliferation with an increase in Egr-1. Immature B lymphoma cells that express Egr-1 constitutiv...

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Bibliographic Details
Main Authors: Gururajan, Murali, Simmons, Alan, Dasu, Trivikram, Spear, Brett T., Calulot, Chris, Robertson, Darrell A., Wiest, David L., Monroe, John G., Bondada, Subbarao
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592513/
https://ncbi.nlm.nih.gov/pubmed/18802061
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