Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques.

Vibrio cholerae O1 A-B- vaccine strain JBK 70 and A-B+ CVD 101 prepared by recombinant DNA techniques from pathogenic EI Tor Inaba N16961 and classical Ogawa 395, respectively, were fed to 38 volunteers in single doses of 10(4) to 10(10). Although severe diarrhea did not occur in any vaccine, more t...

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Publicat a:Infect Immun
Autors principals: Levine, M M, Kaper, J B, Herrington, D, Losonsky, G, Morris, J G, Clements, M L, Black, R E, Tall, B, Hall, R
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259251/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3335402/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.1.161-167.1988
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