Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques.

Vibrio cholerae O1 A-B- vaccine strain JBK 70 and A-B+ CVD 101 prepared by recombinant DNA techniques from pathogenic EI Tor Inaba N16961 and classical Ogawa 395, respectively, were fed to 38 volunteers in single doses of 10(4) to 10(10). Although severe diarrhea did not occur in any vaccine, more t...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Levine, M M, Kaper, J B, Herrington, D, Losonsky, G, Morris, J G, Clements, M L, Black, R E, Tall, B, Hall, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3335402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.1.161-167.1988
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