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Sodium selenite induces apoptosis by generation of superoxide via the mitochondrial-dependent pathway in human prostate cancer cells

PURPOSE: Studies have demonstrated that selenium supplementation reduces the incidence of cancer, particularly prostate cancer. Evidence from experimental studies suggests that apoptosis is a key event in cancer chemoprevention by selenium and reactive oxygen species play a role in induction of apop...

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Bibliographic Details
Main Authors: Xiang, Nong, Zhao, Rui, Zhong, Weixiong
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592502/
https://ncbi.nlm.nih.gov/pubmed/18379781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0745-3
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