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Lipopolysaccharide phase variation determines the complement-mediated serum susceptibility of Coxiella burnetii.

Phase variation of Coxiella burnetii is due to variation of the lipopolysaccharide (LPS), a phenomenon analogous to smooth-to-rough LPS variation of gram-negative enteric bacteria. Virulent enterobacteria usually have a smooth LPS and resist serum killing, whereas avirulent rough LPS mutants are sen...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Vishwanath, S, Hackstadt, T
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3335408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.56.1.40-44.1988
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