Global DNA Hypomethylation Is Associated with High Serum-Persistent Organic Pollutants in Greenlandic Inuit

BACKGROUND: Persistent organic pollutants (POPs) may influence epigenetic mechanisms; therefore, they could affect chromosomal stability and gene expression. DNA methylation, an epigenetic mechanism, has been associated with cancer initiation and progression. Greenlandic Inuit have some of the highe...

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Главные авторы: Rusiecki, Jennifer A., Baccarelli, Andrea, Bollati, Valentina, Tarantini, Letizia, Moore, Lee E., Bonefeld-Jorgensen, Eva C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Institute of Environmental Health Sciences 2008
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592276/
https://ncbi.nlm.nih.gov/pubmed/19057709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11338
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