Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Reprogramming of Metabolism and Alters the Response to a High-Fat Diet in Adulthood

BACKGROUND: Developmental exposures to organophosphate pesticides are virtually ubiquitous. These agents are neurotoxicants, but recent evidence also points to lasting effects on metabolism. OBJECTIVES: We administered parathion to neonatal rats. In adulthood, we assessed the impact on weight gain,...

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Main Authors: Lassiter, T. Leon, Ryde, Ian T., MacKillop, Emiko A., Brown, Kathleen K., Levin, Edward D., Seidler, Frederic J., Slotkin, Theodore A.
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592263/
https://ncbi.nlm.nih.gov/pubmed/19057696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11673
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