Inability to express fimbriae results in impaired ability of Haemophilus influenzae b to colonize the nasopharynx.

We cloned into the structural fimbrial subunit gene from a fimbriated Haemophilus influenzae b a 1.5-kb kanamycin resistance gene. The resultant strain (RKAW5) was tested by Southern analysis, hemagglutination, and electron-micrographic examination to confirm gene inactivation. In comparison with th...

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Bibliographic Details
Main Authors: Weber, A, Harris, K, Lohrke, S, Forney, L, Smith, A L
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC259107/
https://ncbi.nlm.nih.gov/pubmed/1682268
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