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The interaction of CK2α and CK2β, the subunits of protein kinase CK2, requires CK2β in a preformed conformation and is enthalpically driven

The protein kinase CK2 (former name: “casein kinase 2”) predominantly occurs as a heterotetrameric holoenzyme composed of two catalytic chains (CK2α) and two noncatalytic subunits (CK2β). The CK2β subunits form a stable dimer to which the CK2α monomers are attached independently. In contrast to the...

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Autors principals: Raaf, Jennifer, Brunstein, Elena, Issinger, Olaf-Georg, Niefind, Karsten
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590923/
https://ncbi.nlm.nih.gov/pubmed/18824508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037770.108
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