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Association of a null allele of SPRN with variant Creutzfeldt–Jakob disease
BACKGROUND: No susceptibility genes have been identified in human prion disase, apart from the prion protein gene (PRNP). The gene SPRN, encodes Shadoo (Sho, shadow of prion protein) which has protein homology and possible functional links with the prion protein. METHODS: A genetic screen was carrie...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMJ Publishing Group
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590874/ https://ncbi.nlm.nih.gov/pubmed/18805828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2008.061804 |
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