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Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption.

Pathogenic Yersinia spp., including the etiological agent of plague, Y. pestis, all carry a common plasmid that encodes a number of essential virulence determinants, the Yop proteins. One of these, YopE, has been shown to be involved in the obstruction of the primary host defense by a molecular mech...

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Bibliographic Details
Main Authors: Rosqvist, R, Forsberg, A, Wolf-Watz, H
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC259078/
https://ncbi.nlm.nih.gov/pubmed/1937815
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