Immunization of guinea pigs with recombinant TmpB antigen induces protection against challenge infection with Treponema pallidum Nichols.

Treponema pallidum-susceptible guinea pigs of strain C4D were immunized with recombinant T. pallidum antigens TmpA, TmpB, TmpC, and TmpA plus TmpB plus TmpC; with Escherichia coli membranes; or with adjuvant alone. Animals in groups of five received six immunizing injections, each of 100 micrograms...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Wicher, K, Schouls, L M, Wicher, V, Van Embden, J D, Nakeeb, S S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1937794/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.12.4343-4348.1991
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