The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is antigenic in human infections.

Antibodies against the major cysteine proteinase (cruzipain) from Trypanosoma cruzi were detected in human sera obtained from patients with chronic Chagas' disease. Not only the intact 60-kDa enzyme but also its 25-kDa self-proteolysis fragment are antigenic in vivo. Although T. cruzi antigens...

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Udgivet i:Infect Immun
Main Authors: Martinez, J, Campetella, O, Frasch, A C, Cazzulo, J J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1937786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.11.4275-4277.1991
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