Identification of Mycobacterium leprae antigens from a cosmid library: characterization of a 15-kilodalton antigen that is recognized by both the humoral and cellular immune systems in leprosy patients.

Screening of the Mycobacterium leprae cosmid library with pooled sera from lepromatous leprosy (LL) patients by a colony immunoblot technique resulted in the identification of about 100 colonies that produced immunologically reactive proteins. Twenty-four of these clones were purified, analyzed, and...

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Pubblicato in:	Infect Immun
Autori principali:	Sela, S, Thole, J E, Ottenhoff, T H, Clark-Curtiss, J E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1840579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.11.4117-4124.1991
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