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The GABA hypothesis of the pathogenesis of hepatic encephalopathy: current status.

Gamma-aminobutyric acid (GABA), the principal inhibitory neurotransmitter of the mammalian brain, can induce coma. Outside the central nervous system it is synthesized by gut bacteria and catabolized largely in the liver. GABA and its agonists, as well as benzodiazepines and barbiturates, induce neu...

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Detalhes bibliográficos
Main Authors: Jones, E. A., Schafer, D. F., Ferenci, P., Pappas, S. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Yale Journal of Biology and Medicine 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2589853/
https://ncbi.nlm.nih.gov/pubmed/6093394
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