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MDHM, a macrophage-stimulatory product of Mycoplasma fermentans, leads to in vitro interleukin-1 (IL-1), IL-6, tumor necrosis factor, and prostaglandin production and is pyrogenic in rabbits.

Mycoplasma fermentans-derived high-molecular-weight material (MDHM) was originally discovered because of its capacity to generate, through the induction of monokine synthesis, cytolytic T lymphocytes in concanavalin A-stimulated thymocyte cultures. This study shows that MDHM-activated macrophages no...

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Publicado en:Infect Immun
Autores principales: Mühlradt, P F, Schade, U
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258984/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1937755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.11.3969-3974.1991
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