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Prevention of murine cerebral malaria by a stable prostacyclin analog.

Iloprost, a synthetic prostacyclin analog, successfully prevents the development of cerebral malaria in mice. Malaria antigen-induced tumor necrosis factor (TNF) production could be inhibited by iloprost in vitro and in vivo. Northern analysis of TNF mRNA revealed that malaria antigen-induced TNF ex...

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Detalhes bibliográficos
Main Authors: Sliwa, K, Grundmann, H J, Neifer, S, Chaves, M F, Sahlmüller, G, Blitstein-Willinger, E, Bienzle, U, Kremsner, P G
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC258963/
https://ncbi.nlm.nih.gov/pubmed/1716616
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