Cytokine response by human monocytes to Clostridium difficile toxin A and toxin B.

Clostridium difficile toxins A and B isolated from strain VPI 10463 were tested for induction of cytokine release by human monocytes. Toxin B at 10(-12) M activated human monocytes as measured by release of interleukin-1 (IL-1), tumor necrosis factor (TNF), or IL-6. These effects of toxin B were hea...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Flegel, W A, Müller, F, Däubener, W, Fischer, H G, Hadding, U, Northoff, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1910012/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3659-3666.1991
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