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Mechanisms of hepatic transport of cyclosporin A: an explanation for its cholestatic action?

The hepatic transport of the immunosuppressive Cyclosporin A (CyA) was studied using liposomal phospholipid membranes, freshly isolated rat hepatocytes and bile canalicular plasma membrane vesicles from rat liver. The Na(+)-dependent, saturable uptake of the bile acid 3H-taurocholate into isolated r...

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Detalhes bibliográficos
Main Authors: Fricker, G., Fahr, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Yale Journal of Biology and Medicine 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2589335/
https://ncbi.nlm.nih.gov/pubmed/9626758
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