Construction and expression of plasmids containing mutated diphtheria toxin A-chain-coding sequences.

We previously demonstrated that cells can be killed through transfection of an expression plasmid that encodes the diphtheria toxin A-chain fragment (DT-A). This report describes the construction of expression plasmids containing three mutant DT-A-coding sequences substituting glutamic acid 148 with...

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Bibliografiske detaljer
Main Authors: Fisher, K S, Maxwell, I H, Murphy, J R, Collier, J, Glode, L M
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC258921/
https://ncbi.nlm.nih.gov/pubmed/1894362
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