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Suppression by Trypanosoma brucei rhodesiense of the capacities of human T lymphocytes to express interleukin-2 receptors and proliferate after mitogenic stimulation.

We studied the suppressive effects induced in phytohemagglutinin (PHA)-stimulated human peripheral blood mononuclear cells (PBMC) by purified blood forms of Trypanosoma brucei rhodesiense. The parasite was found to markedly impair lymphocyte proliferation (measured in terms of [3H]thymidine incorpor...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Kierszenbaum, F, Muthukkumar, S, Beltz, L A, Sztein, M B
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1894358/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3518-3522.1991
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