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Topoisomerase 3α and RMI1 Suppress Somatic Crossovers and Are Essential for Resolution of Meiotic Recombination Intermediates in Arabidopsis thaliana

Topoisomerases are enzymes with crucial functions in DNA metabolism. They are ubiquitously present in prokaryotes and eukaryotes and modify the steady-state level of DNA supercoiling. Biochemical analyses indicate that Topoisomerase 3α (TOP3α) functions together with a RecQ DNA helicase and a third...

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Detalhes bibliográficos
Main Authors: Hartung, Frank, Suer, Stefanie, Knoll, Alexander, Wurz-Wildersinn, Rebecca, Puchta, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588661/
https://ncbi.nlm.nih.gov/pubmed/19096507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000285
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