Antibody-secreting peripheral blood lymphocytes induced by immunization with a conjugate consisting of Streptococcus pneumoniae type 12F polysaccharide and diphtheria toxoid.

Healthy adult volunteers were injected either with one of two conjugates composed of Streptococcus pneumoniae type 12F polysaccharide (Pn12F) covalently coupled to diphtheria toxoid or with Pn12F alone (as a component of Pnu-Imune, a 23-valent pneumococcus vaccine). The conjugates induced Pn12F-spec...

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Publicado en:	Infect Immun
Autores principales:	Lue, C, Prince, S J, Fattom, A, Schneerson, R, Robbins, J B, Mestecky, J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1990
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2370107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.8.2547-2554.1990
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