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eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications

Temporally precise inhibition of distinct cell types in the intact nervous system has been enabled by the microbial halorhodopsin NpHR, a fast light-activated electrogenic Cl(−) pump. While neurons can be optically hyperpolarized and inhibited from firing action potentials at moderate NpHR expressio...

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Detalhes bibliográficos
Main Authors: Gradinaru, Viviana, Thompson, Kimberly R., Deisseroth, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588488/
https://ncbi.nlm.nih.gov/pubmed/18677566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11068-008-9027-6
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