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eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications
Temporally precise inhibition of distinct cell types in the intact nervous system has been enabled by the microbial halorhodopsin NpHR, a fast light-activated electrogenic Cl(−) pump. While neurons can be optically hyperpolarized and inhibited from firing action potentials at moderate NpHR expressio...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2588488/ https://ncbi.nlm.nih.gov/pubmed/18677566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11068-008-9027-6 |
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