Multiple interactions between the alpha(2C)- and beta(1)-adrenergic receptors influence heart failure survival

BACKGROUND: Persistent stimulation of cardiac β(1)-adrenergic receptors by endogenous norepinephrine promotes heart failure progression. Polymorphisms of this gene are known to alter receptor function or expression, as are polymorphisms of the α(2C)-adrenergic receptor, which regulates norepinephrin...

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Detalhes bibliográficos
Main Authors: Kardia, Sharon LR, Kelly, Reagan J, Keddache, Mehdi A, Aronow, Bruce J, Grabowski, Gregory A, Hahn, Harvey S, Case, Karen L, Wagoner, Lynne E, Dorn, Gerald W, Liggett, Stephen B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588439/
https://ncbi.nlm.nih.gov/pubmed/18947427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-93
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