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Interaction of Clostridium difficile toxin A with cultured cells: cytoskeletal changes and nuclear polarization.

Experiments done on in vitro-cultured cells exposed to toxin A from C. difficile showed a series of cytopathologic changes leading to cell retraction and rounding accompanied by the marginalization of the nucleus, which localized at one pole of the cell. Cytoskeleton appeared to be strongly involved...

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Detalles Bibliográficos
Main Authors: Fiorentini, C, Malorni, W, Paradisi, S, Giuliano, M, Mastrantonio, P, Donelli, G
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC258816/
https://ncbi.nlm.nih.gov/pubmed/2114363
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