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Malleable Machines in Transcription Regulation: The Mediator Complex
The Mediator complex provides an interface between gene-specific regulatory proteins and the general transcription machinery including RNA polymerase II (RNAP II). The complex has a modular architecture (Head, Middle, and Tail) and cryoelectron microscopy analysis suggested that it undergoes dramati...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2588115/ https://ncbi.nlm.nih.gov/pubmed/19096501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000243 |
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