Loss of Vitamin D Receptor Produces Polyuria by Increasing Thirst

Vitamin D receptor (VDR)-null mice develop polyuria, but the underlying mechanism remains unknown. In this study, we investigated the relationship between vitamin D and homeostasis of water and electrolytes. VDR-null mice had polyuria, but the urine osmolarity was normal as a result of high salt exc...

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Detalhes bibliográficos
Main Authors: Kong, Juan, Zhang, Zhongyi, Li, Dongdong, Wong, Kari E., Zhang, Yan, Szeto, Frances L., Musch, Mark W., Li, Yan Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588110/
https://ncbi.nlm.nih.gov/pubmed/18832438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008010011
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