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Upregulation of Ionotropic Glutamate Receptor Subunits within Specific Mesocorticolimbic Regions during Chronic Nicotine Self-Administration

Nicotine, an addictive substance, is the major psychoactive component in cigarette smoke. Both α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid and N-methyl-(D)-aspartate (NMDA) receptors are essential for the acute stimulative effects of nicotine on the mesocorticolimbic dopamine system, yet l...

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Main Authors: Wang, Fan, Chen, Hao, Steketee, Jeffery D, Sharp, Burt M
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587993/
https://ncbi.nlm.nih.gov/pubmed/16452988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301033
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