AIRE regulates T-cell-independent B-cell responses through BAFF

Autoimmune polyendocrine syndrome type I (APS I) results in multiple endocrine organ destruction and is caused by mutations in the autoimmune regulator gene (AIRE). APS I is characterized by circulating tissue-specific autoantibodies, and the presence of these antibodies is often predictive of organ...

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Bibliografiske detaljer
Main Authors: Lindh, Emma, Lind, Sara M., Lindmark, Evelina, Hässler, Signe, Perheentupa, Jaakko, Peltonen, Leena, Winqvist, Ola, Karlsson, Mikael C. I.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587634/
https://ncbi.nlm.nih.gov/pubmed/19011083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808205105
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