Human multipotent stromal cells from bone marrow and microRNA: Regulation of differentiation and leukemia inhibitory factor expression

We observed that microRNAs (miRNAs) that regulate differentiation in a variety of simpler systems also regulate differentiation of human multipotent stromal cells (hMSCs) from bone marrow. Differentiation of hMSCs into osteoblasts and adipocytes was inhibited by using lentiviruses expressing shRNAs...

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Main Authors: Oskowitz, Adam Z., Lu, Jun, Penfornis, Patrice, Ylostalo, Joni, McBride, Jane, Flemington, Erik K., Prockop, Darwin J., Pochampally, Radhika
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587615/
https://ncbi.nlm.nih.gov/pubmed/19011087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809807105
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