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Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein

The far upstream element (FUSE) binding protein (FBP), a single-stranded nucleic acid binding protein, is recruited to the c-myc promoter after melting of FUSE by transcriptionally generated dynamic supercoils. Via interactions with TFIIH and FBP-interacting repressor (FIR), FBP modulates c-myc tran...

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Autori principali: Benjamin, Lawrence R., Chung, Hye-Jung, Sanford, Suzanne, Kouzine, Fedor, Liu, Juhong, Levens, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587613/
https://ncbi.nlm.nih.gov/pubmed/19015535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803279105
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