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Helicobacter pylori urease activity is toxic to human gastric epithelial cells.

A human gastric adenocarcinoma cell line was used to evaluate the contribution of urease from Helicobacter (formerly Campylobacter) pylori to its cytotoxicity. Gastric cells cultured in medium supplemented with 20 mM urea were exposed to 5 x 10(6) CFU of H. pylori per ml with or without the addition...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Smoot, D T, Mobley, H L, Chippendale, G R, Lewison, J F, Resau, J H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2341188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.6.1992-1994.1990
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